Ann Home is on Trương Định street in District 1, the central district of Ho Chi Minh City. Ben Thanh Market, one of the city's best-known markets, is 250 m away, and its stalls sell clothing, handicrafts and street food. Sri Mariamman Temple, a Hindu temple with colourful sculptures on its facade, is just around the corner. Trung Nguyên Legend Café and Japankuru, both 50 m away, are among the nearest places for a coffee.
Tan Son Nhat International Airport, in the Tan Binh district north-west of the centre, is 5.3 km from Ann Home, and Saigon Railway Station is 2.2 km away, where trains from the north and the coast arrive. An airport shuttle is among the hotel's services. The Bến xe buýt Sài Gòn bus station is 850 m away, and for the last stretch from the station or the airport a taxi to the door is the simplest option. Ride-hailing cars and taxis are also the easiest way to reach the farther parts of the city from here.
Independence Palace, the former presidential palace open to visitors, is 500 m away, and the War Remnants Museum, which documents the Vietnam War, is 850 m. Tao Dan Park, 400 m from the hotel, is a shaded place for a walk, and Nha Rong Wharf is 1.3 km away on the Saigon River. The Ho Chi Minh City Fine Arts Museum, housed in a colonial-era building, is a short walk away, and the streets around Ben Thanh are busy with evening crowds.